India’s ‘Munjaru bride’: Weight loss injections become part of pre-wedding preparations

Rishika Saddam

Pre-wedding weight loss packages with Indian clinics market Monjaro and Vigoi India’s obesity drug market to reach $860.34 million by 2030 Drug regulators are raising concerns about potential abuse as local drugmakers launch cheaper weight-loss drugs HYDERABAD, India, April 3 (Reuters) – Soon-to-be brides and grooms looking for shortcuts to shed pounds before the big … Read more

Can a “supropiod” treat pain without opioids? The Nature paper says maybe.

Can a "supropiod" treat pain without opioids? The Nature paper says maybe.

I’ve written recently about nitazines ( here and here ), a class of deadly synthetic opioids that have started showing up in the street drug supply over the past few years. Just what we don’t need. These bad boys are extraordinarily potent—often more so than fentanyl—and easy to make using common laboratory chemicals. In other … Read more

Illegal fentanyl supply in the United States increases the risk of overdose and acute withdrawal syndrome

Percent of Opioid-Positive Drug Products and Paraphernalia Samples Also Positive for Meditomidine at 20 Sentinel Sites: US Region, July 2025–December 2025 (Interim Data) b,c

Despite US drug overdose deaths declining from 2022 to 2025, the supply of illegal drugs is unpredictable. Illicitly manufactured fentanyl is involved in many deaths and is frequently mixed with other drugs such as benzodiazepines or xylazine. Meditomidine, an alpha-2 adrenergic agonist sedative, more potent and longer-acting than clonidine and xylazine, was first identified in … Read more

GLP-1 pills vs. Shots: Which is easier, cheaper, and more effective for weight loss?

GLP-1s are now available as pills or shots. Credits: Design by Health; Getty Images

Medically reviewed by Lindsay Cook, PharmD GLP-1s are now available as pills or shots.Credits: Design by Health; Getty Images GLP-1 medications are now available as pills and injections, providing more options for weight loss treatment. The two forms work similarly and have comparable results, but differ in dosage, absorption, and regimens. Experts say the best … Read more

Woman says she lost 60 pounds on new Lilly weight loss pill: ‘Big difference’

Maggie Linton joined Lilly's clinical trials for its new GLP-1 pill, Foundio.

Maggie Linton had never liked injections, so when she heard that Eli Lilly was working on a GLP-1 pill, she was eager to sign up for a clinical trial and put the new drug to the test. Linton took a daily pill called Foundive for nearly two years and said she lost about 60 pounds. … Read more

APTOPIX Ancient Iranian festival

APTOPIX Ancient Iranian festival

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The new opioid painkiller has surprisingly few side effects

The new opioid painkiller has surprisingly few side effects

N-desethyl-fluornitrazene, or DFNZ structure.” class=”w-100″ decoding=”async”/> Structure of N-Deacetyl-fluoronitrazine, or DFNZ. Using the long-abandoned class of opioids as a starting point, scientists have discovered opioid painkillers that do not have the typical side effects of this class of drugs (nature 2026, DOI: 10.1038/s41586-026-10299-9). In tests with mice, the molecule – known as N— desethyl-fluornitrazene, or … Read more

Drug shortages drive record prices of essential drugs in Iran

Drug shortages drive record prices of essential drugs in Iran

Being born as a scientist in the Middle East, and especially in Iran, is a legacy of obstacles to your education, your mobility, and often your sense of belonging before publishing your first paper. For many students, the obstacles start early. Access to higher education depends on geography, religion, ethnicity or family background. Some research … Read more

Editorial: Pharma reluctant to serve Europe to get rid of MFN drug prices

Editorial: Pharma reluctant to serve Europe to get rid of MFN drug prices

Drug industry giants managed last year to allay some concerns about drug prices. Pharmacy Benefit Managerswhile publicly agreeing to lower some rates with the White House. These flashy announcements helped create the illusion that action was being taken to help Americans pay less for their prescription drugs, and the pharmaceutical industry received some improvement in … Read more

Liposyn reports top-line safety and efficacy results for LPCN 1154 in patients with postpartum depression

(PRNewsfoto/Lipocine Inc.)

In a phase 3 study population of patients with PPD (N = 90), LPCN 1154 did not demonstrate a statistically significant reduction from baseline in the HAM-D17 total score at 60 hours (primary endpoint) compared to placebo. The primary endpoint was not met In a post hoc analysis of participants (n = 54) with a … Read more