Illegal fentanyl supply in the United States increases the risk of overdose and acute withdrawal syndrome

Percent of Opioid-Positive Drug Products and Paraphernalia Samples Also Positive for Meditomidine at 20 Sentinel Sites: US Region, July 2025–December 2025 (Interim Data) b,c

Despite US drug overdose deaths declining from 2022 to 2025, the supply of illegal drugs is unpredictable. Illicitly manufactured fentanyl is involved in many deaths and is frequently mixed with other drugs such as benzodiazepines or xylazine. Meditomidine, an alpha-2 adrenergic agonist sedative, more potent and longer-acting than clonidine and xylazine, was first identified in … Read more

‘When the sirens go off, it feels like a heart attack’: Anxiety increases during war

A shelter in Tel Aviv during the Hari Roar days of alarm

“I immediately experience crying and shaking, feeling like I’m having a heart attack, and the crying just won’t stop.” 57-year-old Ayala Bin Haroush, a resident of Nahariya, told about anxiety attacks. In the last two and a half years. “It’s changed my life, it’s unbearable. Everything hurts. When my husband isn’t home, I live in … Read more

March Madness increases the risk of problem gambling, especially for young people

March Madness increases the risk of problem gambling, especially for young people

March Madness this week features a collection of 67 single-elimination basketball games that will not only win championships over 2½ weeks, but also billions of dollars in sports betting. Experts say young people are especially at risk of developing gambling problems. According to a 2024 survey conducted by Fairleigh Dickinson University, 24% of men reported … Read more